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目的 探讨基于双层探测器光谱CT的不同成像方案在民航飞行员微小肾结石鉴别中的图像质量、辐射剂量及诊断效能差异。方法 回顾性纳入2024年5月至2025年7月于民航总医院接受泌尿系压腹增强CT检查的120例肾结石(直径≤5 mm)民航飞行员,采用随机数字表法将其随机分为两组:对照组和光谱组,每组60例。光谱组重建40 keV与55ke V虚拟单能量图像,对照组重建传统图像。以输尿管电子纤维软镜检查为金标准,评价两组图像质量评分及结石检出率。结果 40 keV图像为最佳虚拟单能量图像。光谱组40 keV图像质量与对照组传统图像比较,差异无统计学意义(P>0.05)。对照组诊断肾结石的准确率、敏感度和特异度分别为93.22%、92.86%和94.12%;光谱组的准确率、敏感度和特异度分别为93.86%、94.12%和93.10%。结论 双层探测器光谱CT 40 keV虚拟单能量图像在保证图像质量的同时,约可降低30%辐射剂量与50%碘对比剂用量,在飞行员微小肾结石筛查中具有重要的临床价值。
Abstract:Objective To explore the differences in image quality, radiation dose and diagnostic efficacy of different imaging protocols based on dual-layer detector spectral CT in the differentiation of small kidney stones(diameter≤5 mm) in civil aviation pilots. Methods A total of 120 civil aviation pilots with kidney stones(diameter ≤ 5 mm) who underwent enhanced CT urography with abdominal compression in our hospital from May 2024 to July 2025 were retrospectively included. They were divided into the control group and the spectral group, with 60 cases in each group. The spectral group underwent reconstruction of 40 keV and 55 keV virtual monoenergetic images(VMI), while the control group underwent reconstruction of conventional images. Using ureteroscopic electronic flexible ureteroscopy as the gold standard, image quality scores and stone detection rates were evaluated for the two groups. Results The 40 keV images were consistently identified as the optimal VMI. There was no statistically significant difference in image quality between the 40 keV images in the spectral group and the conventional images in the control group(P>0.05). The accuracy, sensitivity, and specificity for the control group were 93.22%, 92.86%, and 94.12% respectively, while they were 93.86%, 94.12%, and 93.10% respectively for the spectral group. Conclusion The 40 keV VMIs of the dual-layer detector spectral CT can significantly reduce the radiation dose by approximately 30% and the amount of iodine contrast agent by 50% while ensuring image quality. It has significant clinical value for small kidney stones screening in pilots.
[1]中国民用航空局飞行标准司.空勤人员和空中交通管制员体检鉴定医学标准:AC-67FS-001R2[S].北京:中国民用航空局, 2025.
[2]ZHANG G, ZHANG X, XU L, et al. Value of deep learning reconstruction at ultra-low-dose CT for evaluation of urolithiasis[J]. Eur Radiol,2022, 32(9):5954-5963. DOI:10.1007/s00330-022-08739-x.
[3]ASCENTI G, CICERO G, BERTELLI E, et al. CT-urography:a nationwide survey by the Italian Board of Urogenital Radiology[J]. Radiol Med, 2022,127(6):577-588. DOI:10.1007/s11547-022-01488-3.
[4]BECKETT KR, MORIARITY AK, LANGER JM. Safe use of contrast media:what the radiologist needs to know[J]. Radiographics,2015, 35(6):1738-1750. DOI:10.1148/rg.2015150033.
[5]YANG P, ZHAO R, DENG W, et al. Feasibility and accuracy of coronary artery calcium score on virtual non-contrast images derived from a dual-layer spectral detector CT:A retrospectivemulticenter study[J]. Front Cardiovasc Med, 2023, 10:1114058.DOI:10.3389/fcvm.2023.1114058.
[6]于宝玉,张斌,张博洋,等.低剂量CT联合图像域迭代重建算法对泌尿系结石的诊断值及结石成分分析[J].中国医学前沿杂志(电子版), 2022, 14(10):31-35.DOI:10.12037/YXQY.2022.10-07.
[7]GALTUNG KF, LAURITZEN PM, SANDBAEK G, et al. Urinary stone assessment in a single-phase may replace the unenhanced and multiphase computed tomography protocol in painless visible haematuria[J]. Scand J Urol, 2024, 59:147-155. DOI:10.2340/sju.v59.40679.
[8]EXPERT PANEL ON UROLOGICAL IMAGING, GUPTA RT, KALISZ K, et al. ACR Appropriateness Criteria®acute onset flank pain-suspicion of stone disease(urolithiasis)[J]. J Am Coll Radiol, 2023, 20(11S):S315-S328. DOI:10.1016/j.jacr.2023.08.020.
[9]朱海峰,崔亮,汪庆,等.民航飞行员压腹增强CT诊断肾小结石的准确性探讨[J].中华空航天医学杂志, 2021, 32(3):152-154. DOI:10.3760/cma.j.cn113854-20200325-00036.
[10]TORRES MJ, TRAUTMANN A, BÖHM I, et al. Practice parameters for diagnosing and managing iodinated contrast media hypersensitivity[J]. Allergy, 2021,76(5):1325-1339. DOI:10.1111/all.14656.
[11]SMITH-BINDMAN R, CHU PW, AZMAN FIRDAUS H, et al.Projected lifetime cancer risks from current computed tomography imaging[J]. JAMA Intern Med, 2025, 185(6):710-719.DOI:10.1001/jamainternmed.2025.0505.
[12]Mitchell AM, Jones AE, Tumlin JA, et al. Incidence of contrast-induced nephropathy aftercontrast-enhanced computed tomography in the outpatient setting[J]. Clin J Am Soc Nephrol,2010, 5(1):4-9. DOI:10.2215/cjn.05200709.
[13]EULER A, WULLSCHLEGER S, SARTORETTI T, et al. Dual-energy CT kidney stone characterization-can diagnostic accuracy be achieved at low radiation dose?[J]. Eur Radiol, 2023, 33(9):6238-6244.DOI:10.1007/s00330-023-09569-1.
[14]LI X, ZHANG J, YU D, et al. Flexible ureteroscopy in Chinese air force pilots with renal calculi:a cohort study at a single medical centre[J]. BMJ Mil Health, 2025, 171(6):555-560.DOI:10.1136/military-2024-002712.
[15]ALLPHIN AJ, CLARK DP, THUERING T, et al. Micro-CT imaging of multiple K-edge elements using GaAs and CdTe photon counting detectors[J].Phys Med Biol, 2023, 68(8):10. DOI:10.1088/1361-6560/acc77e.
[16]MCCOLLOUGH CH, LENG S, YU L, et al. Principles, technical approaches, and clinicalapplications[J]. Radiology, 2015, 276(3):637-653. DOI:10.1148/radiol.2015142631.
[17]NAGAYAMA Y, NAKAURA T, ODA S, et al. Dual-layer DECT for multiphasic hepatic CT with 50 percent iodine load:a matched-pair comparison with a 120 kVp protocol[J]. Eur Radiol, 2018, 28(4):1719-1730. DOI:10.1007/s00330-017-5114-3.
[18]YUAN R, SHUMAN WP, EARLS JP, et al. Reduced iodine load at CT pulmonary angiography with dual-energy monochromatic imaging:comparison with standard CT pulmonary angiography-a prospective randomized trial[J]. Radiology, 2012, 262(1):290-297. DOI:10.1148/radiol.11110648.
[19]FAHRNI G, MINGAS T, DELIESSCHE A, et al. Low-iodine 40-keV virtual monoenergetic CT angiography of the lower extremities[J]. Front Cardiovasc Med, 2023, 10:1276738. DOI:10.3389/fcvm.2023.1276738.
[20]WANNASOPHA Y, LEESMIDT K, SRISUWAN T, et al. Value of low-ke V virtual monoenergetic plus dual-energy computed tomographic imaging for detection of acute pulmonary embolism[J]. PLoS One, 2022,17(11):e0277060. DOI:10.1371/journal.pone.0277060.
基本信息:
DOI:10.16289/j.cnki.1002-0837.2026.01005
中图分类号:R856.5
引用信息:
[1]杨杉,朱海峰,王玉婕,等.双层探测器光谱CT不同成像方案对民航飞行员微小肾结石诊断价值的探讨[J].航天医学与医学工程,2026,37(01):24-29.DOI:10.16289/j.cnki.1002-0837.2026.01005.