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近年来，随着深空探索任务的不断推进，航天员在太空中长期暴露于多种复合极端因素，如微重力、空间辐射、昼夜节律紊乱、密闭隔离等极端复合环境。这些因素极易诱发航天员脑功能异常，表现为认知功能下降、情绪障碍、睡眠障碍及神经炎症反应等。中医药以“整体调节”“辨证施治”为核心理念，具备多靶点调控、系统协调等特点，近年来在脑功能保护研究中引发广泛关注。本文系统综述了中医药及其相关技术在载人航天飞行与模拟航天环境模型中对脑功能障碍的防护应用及研究进展，探讨其作用机制与发展前景，以期为航天员脑健康防护提供参考，并为未来深空任务中的中医药精准干预与系统化防护方案的设计奠定理论基础。
Abstract：In recent years,with the continuous advancement of deep space exploration missions,astronauts have been increasingly exposed to complex and extreme environmental factors in space,such as microgravity,space radiation,circadian rhythm disruption,and confined isolation.These conditions can easily induce brain dysfunction in astronauts,manifesting as cognitive decline,emotional disturbances,sleep disorders,and neuroinflammatory responses.Traditional Chinese Medicine(TCM),characterized by its holistic regulation and syndrome differentiation-based treatment principles,exhibits multi-target regulation and systemic coordination,and has attracted growing attention in the field of brain function protection.This study systematically reviews the protective applications and research progress of TCM and related techniques in both actual spaceflight missions and simulated space environment models against brain functional disorders.The underlying mechanisms and future prospects are discussed,with the aim of providing insights for safeguarding astronauts' brain health and laying a theoretical foundation for the precise intervention and systematic protection strategies of TCM in future deep space missions.
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基本信息:
DOI：10.16289/j.cnki.1002-0837.2025.05015
中图分类号:R856
引用信息:
[1]盛欣仪,孟靓辉,罗彦,等.中医药在载人航天脑保护中的应用研究进展[J].航天医学与医学工程,2025,36(05):479-485.DOI:10.16289/j.cnki.1002-0837.2025.05015.
基金信息:
国家自然科学基金（82371886）; 天津市自然科学基金（24JCQNJC01080）